Lease expire date Lease Expiration Date1 Vesting period of PRSUs after acceptance Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1 Performance-based restricted stock units Performance Based Restricted Stock Units [Member] Performance-based restricted stock units. Number of tranches Number Of Tranches Number of tranches. Lease commencement date Lease Commencement Date Lease commencement date. Significant Risks and Uncertainties Significant Risks And Uncertainties Policy [Text Block] Disclosure of accounting policy for significant risks and uncertainties. Valuation Approach and Technique Valuation Technique [Domain] Sale Of Future Royalties [Abstract] Sale of future royalties. Expenses Operating Expenses [Abstract] Loss from operations Operating Income Loss Entity Emerging Growth Company Entity Emerging Growth Company Upfront payment from the sale of future royalties Upfront Payment Paid Upfront payment paid. Available for future grant (in shares) Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Common Stock, Value, Issued, Ending Balance Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Total Common stock; $0.0001 par value; 125,000,000 shares authorized; 42,721,566 shares issued and outstanding as of March 31, 2022 and December 31, 2021, respectively Common Stock Value Entity Address, State or Province Entity Address State Or Province Total liabilities Liabilities Risk free interest rate Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Monthly rental rate Monthly Rental Rate Monthly rental rate. Goodwill, Ending Balance Goodwill, Beginning Balance Goodwill, Total Goodwill Goodwill Reverse stock split Stockholders' Equity, Reverse Stock Split Indefinite-lived Intangible Assets Indefinite Lived Intangible Assets By Major Class [Axis] Operating lease liabilities, current Increase Decrease In Operating Lease Liabilities Current Increase (decrease) in operating lease liabilities, current. Weighted average shares outstanding, basic and diluted Weighted average shares of common stock outstanding Weighted Average Number Of Share Outstanding Basic And Diluted Shares Issuable Pursuant to Stock Options Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Roll Forward Annual interest rate on interest expense Annual Interest Rate On Interest Expense Annual interest rate on interest expense. General and Administrative General And Administrative Expense [Member] Weighted-Average Remaining Contractual Term Exercisable (Years) Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1 Research and development costs and other accrued expenses Accrued Research And Development Costs And Other Expenses Current Represents the carrying value, as of the balance sheet date, of obligations incurred through that date and payable for research and development costs. It is used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle, if longer). Significant Accounting Policies Significant Accounting Policies [Text Block] City Area Code City Area Code Summary of Assumptions Used in Black Scholes Model to Estimate Fair Value of Stock Options Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block] Forfeited (in dollars per share) Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price Reconciliation of the Condensed Consolidated Statements of Cash Flows to the Condensed Consolidated Balance Sheets Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents [Abstract] Commitments and contingencies (Note 8) Commitments And Contingencies Class Of Warrant Or Right [Line Items] Class Of Warrant Or Right [Line Items] Securities Excluded from Calculation of Weighted Average Shares Outstanding as their Effect is Antidilutive Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block] Loan and Security Agreement Loan And Security Agreement [Member] Loan and security agreement. Common stock issued and sold Stock Issued During Period Shares New Issues Capitalized Computer Software, Net, Ending Balance Capitalized Computer Software, Net, Beginning Balance Capitalized Computer Software, Net, Total Capitalized software, net Capitalized Computer Software Net Basis of Presentation Basis Of Accounting Policy Policy [Text Block] Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Ending Balance Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Beginning Balance Total cash, cash equivalents and restricted cash Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Income Statement [Abstract] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Net Cash Provided by (Used in) Investing Activities, Total Net cash provided by investing activities Net Cash Provided By Used In Investing Activities General and Administrative Expense, Total General and administrative General And Administrative Expense Common Stock, Shares, Issued, Total Common stock, shares issued Common Stock Shares Issued Proceeds from the sale of future royalties Proceeds From Sale Of Future Royalties Proceeds from the sale of future royalties. Security Exchange Name Security Exchange Name Statistical Measurement Range [Member] Liability related to the sale of future royalties Liability Related To Sale Of Future Royalties Liability related to the sale of future royalties. Measurement Input, Price Volatility Measurement Input Price Volatility [Member] Aggregate principal amount Line Of Credit Facility Maximum Borrowing Capacity Document Period End Date Document Period End Date Income Statement Location Income Statement Location [Axis] Common Stock Warrants Warrant [Member] Related Party Transaction [Axis] Number of shares of common stock authorized Common stock, shares authorized Common Stock Shares Authorized Non-cash interest expense for the sale of future royalties Non Cash Interest Expense For The Sale Of Future Royalties Non-cash interest expense for the sale of future royalties Use of Estimates Use Of Estimates Adjustments to reconcile net loss to net cash used in operating activities: Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Securities outstanding excluded from the calculation of weighted average shares outstanding Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Accrued Expenses and Other Liabilities Accounts Payable And Accrued Liabilities Disclosure [Text Block] Entity Address, Address Line Two Entity Address Address Line2 Current Fiscal Year End Date Current Fiscal Year End Date Net (decrease) increase in cash, cash equivalents and restricted cash Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect Expected life Alternative Investment Measurement Expected Term Alternative investment measurement expected term. Operating lease, cost Operating Lease Cost Sale Of Future Royalties [Table] Sale Of Future Royalties [Table] Sale of future royalties. Counterparty Name Counterparty Name [Axis] Assets Assets [Abstract] 2023 Lessee, Operating Lease, Liability, to be Paid, Year One Accounts Payable, Current, Total Accounts payable Accounts Payable Current Debt Instrument, Name Debt Instrument Name [Domain] Common stock, par value (in dollars per share) Common Stock Par Or Stated Value Per Share Additional Paid in Capital, Common Stock, Ending Balance Additional Paid in Capital, Common Stock, Beginning Balance Additional paid-in capital Additional Paid In Capital Common Stock Number of licenses acquired Number Of Licenses Acquired Number of licenses acquired. Stockholders Equity Note [Abstract] Non-cash incremental stock-based compensation cost Share Based Goods And Services Non Cash Incremental Stock Based Compensation Cost Share based goods and services non cash incremental stock based compensation cost. Document Type Document Type Preferred Stock, Value, Issued, Ending Balance Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Total Preferred stock; $0.0001 par value; 100,000,000 shares authorized; none issued or outstanding as of March 31, 2022 and December 31, 2021, respectively Preferred Stock Value Total Accrued expenses and other current liabilities Accounts Payable And Other Accrued Liabilities Current Schedule of Accrued Expenses and Other Liabilities Schedule Of Accrued Liabilities Table [Text Block] Total current assets Assets Current Sales Agreement Sales Agreement [Member] Sales agreement. Common Stock Options Employee Stock Option Employee Stock Option [Member] Long-term Debt, Type Longterm Debt Type [Domain] Weighted-Average Remaining Contractual Term Outstanding (Years) Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2 Earnings Per Share, Basic and Diluted, Total Net loss per share, basic and diluted Net loss per share of common stock – basic and diluted Earnings Per Share Basic And Diluted Expiration anniversary date of issuance Expiration Anniversary Date Of Issuance Expiration anniversary date of issuance. Leases [Abstract] Antidilutive Securities Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Consolidation Consolidation Policy [Text Block] Common stock, shares outstanding Balance (in shares) Balance (in shares) Common Stock Shares Outstanding Plan Name Plan Name [Axis] Forfeited (in shares) PRSU'S cancelled Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period U S Food and Drug Administration [Member] U S Food And Drug Administration [Member] Total expenses Operating Expenses Measurement Input, Expected Dividend Payment Measurement Input Expected Dividend Payment [Member] Nature Of Operations And Liquidity [Line Items] Nature Of Operations And Liquidity [Line Items] Nature of operations and liquidity. Outstanding at the beginning of period (in dollars per share) Outstanding at the end of the period (in dollars per share) Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Cash flows from operating activities: Net Cash Provided By Used In Operating Activities [Abstract] Future Minimum Sublease Payments Under Non-cancelable Operating Sublease Lessee Operating Lease Liability Maturity Table [Text Block] Common stock exercise price per share Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1 Earnings Per Share [Abstract] Net loss Net loss Net Income Loss Research and Development Research And Development Expense [Member] Document Fiscal Period Focus Document Fiscal Period Focus Accounting Policies [Abstract] 2013 Equity Incentive Plan Twenty Thirteen Equity Incentive Plan [Member] Twenty thirteen equity incentive plan. Entity Address, Address Line One Entity Address Address Line1 Total intrinsic value of the stock options exercised Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value PRSU'S outstanding Outstanding at the beginning of period (in shares) Outstanding at the end of the period (in shares) Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number Total current liabilities Liabilities Current Sale Of Future Royalties [Line Items] Sale Of Future Royalties [Line Items] Sale of future royalties. Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Net loss Profit Loss Entity Address, Postal Zip Code Entity Address Postal Zip Code Title of Individual Title Of Individual [Axis] Nature Of Operations And Liquidity [Table] Nature Of Operations And Liquidity [Table] Disclosure pertaining to nature of operations and liquidity. Total Intrinsic Value Outstanding at the begining of period Total Intrinsic Value Outstanding at the end of period Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value Product and Service Products And Services [Domain] Increase in number of shares authorized for issuance Share Based Compensation Arrangement By Share Based Payment Award Number Of Additional Shares Authorized Collaborative Arrangement and Arrangement Other than Collaborative Arrangements And Nonarrangement Transactions [Member] Lease description Lease Description Lease description. Net cash used in operating activities Net cash used in operating activities Net Cash Provided By Used In Operating Activities Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total Beginning of period End of period Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations Equity Components Statement Equity Components [Axis] Current assets Assets Current [Abstract] Regus Regus [Member] Regus. Entity Registrant Name Entity Registrant Name Stockholders' Equity Stockholders Equity Note Disclosure [Text Block] Entity Interactive Data Current Entity Interactive Data Current Entity Address, City or Town Entity Address City Or Town Term A Loans Term A Loans [Member] Term A loans. Warrant Warrants Not Settleable Cash [Member] Warrants Not Setteleable Cash . Indefinite-lived Intangible Assets, Major Class Name Indefinite Lived Intangible Assets Major Class Name [Domain] Fees paid in connection with the reverse stock split fractional shares Payments of fees paid in connection with reverse stock split fractional shares Payments of Fees Paid in Connection with Reverse Stock Split Fractional Shares Payments of fees paid in connection with reverse stock split fractional shares. Measurement Input, Expected Term Measurement Input Expected Term [Member] Summary of Activity of the Royalty Obligation Summary Of Activity Of The Royalty Obligation Table [Text Block] Summary of activity of the royalty obligation. Expected term (years) Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1 Trading Symbol Trading Symbol Cash flows from investing activities: Net Cash Provided By Used In Investing Activities [Abstract] Upfront payment for royalty interest sold Upfront Payment Upfront payment. Local Phone Number Local Phone Number Total stockholders' (deficit) equity Balance Balance Stockholders Equity Weighted-Average Exercise Price Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Rollforward Preferred Stock, Shares Issued, Total Preferred stock, shares issued Preferred Stock Shares Issued Statistical Measurement Range [Axis] Entity Small Business Entity Small Business Preferred Stock, Shares Outstanding, Ending Balance Preferred Stock, Shares Outstanding, Beginning Balance Preferred stock, shares outstanding Preferred Stock Shares Outstanding APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total Stock-based compensation Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value Credit Facility Credit Facility [Axis] Adjustments due to the rounding impact from the reverse stock split for fractional shares Adjustments to Additional Paid in Capital, Stock Split Sale of stock issue date Sale Of Stock Transaction Date Accrued bonus Accrued Bonuses Current Granted (in dollars per share) Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price Vacation pay Accrued Vacation Current Plan Name Plan Name [Domain] Cash, cash equivalents, restricted cash and marketable securities Cash Cash Equivalents Restricted Cash And Marketable Securities Cash, cash equivalents, restricted cash and marketable securities. Lessee Lease Description [Table] Lessee Lease Description [Table] Prepaid Expense, Current, Total Prepaid expenses and other current assets Prepaid Expense Current Sales of common stock, value Stock Issued During Period Value New Issues Term Loan Notes Payable To Banks [Member] BP Reservoir BP Reservoir [Member] BP Reservoir. Foreign exchange gains (losses) Foreign Currency Transaction Gain (Loss), before Tax, Total Foreign Currency Transaction Gain Loss Before Tax Share-based Payment Arrangement, Noncash Expense, Total Stock-based compensation expense Share Based Compensation Schedule of Stock Option Activity for Employees and Non-Employees Schedule Of Share Based Compensation Stock Options Activity Table [Text Block] Seltorexant Seltorexant [Member] Seltorexant. Restricted cash balances as collateral for corporate credit cards Restricted cash Restricted Cash Current Alternative investment, measurement input Alternative Investment Measurement Input Exercisable at the end of the period (in shares) Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number Net cash (used in) provided by financing activities Net Cash Provided By Used In Financing Activities Commitments And Contingencies Disclosure [Abstract] Total assets Assets Leases Lessee Operating Leases [Text Block] Exercised (in shares) Stock Issued During Period Shares Stock Options Exercised Statement [Line Items] Statement [Line Items] Total liabilities and stockholders' (deficit) equity Liabilities And Stockholders Equity Document Quarterly Report Document Quarterly Report Statement Of Cash Flows [Abstract] Exercise price per unit Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Exercise Price Additional Paid-in Capital Additional Paid In Capital [Member] Title of 12(b) Security Security12b Title Nature Of Operations And Liquidity Disclosure [Abstract] Employees and Non-Employees Stock Option Employees And Non Employees Stock Option [Member] Employees and non-employees stock option. Non-cash interest expense associated with the sale of future royalties Non Cash Interest Expense For Sale Of Future Royalties Amount of non-cash interest expense associated with the sale of future royalties. Award Type Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Vesting percentage Sharebased Compensation Arrangement By Sharebased Payment Award Award Vesting Rights Percentage Investment income Investment Income Interest Sale of Future Royalties Sale Of Future Royalties Disclosure [Text Block] Sale of future royalties. Lease rentable square feet Area Of Real Estate Property Shares issued Granted (in shares) Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross Entity Current Reporting Status Entity Current Reporting Status Valuation Approach and Technique Valuation Technique [Axis] Measurement Input Type Measurement Input Type [Domain] Additional milestone payments Potential Milestone Payments Cash, cash equivalents and restricted cash Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations [Abstract] 2022 Lessee Operating Lease Liability Payments Remainder Of Fiscal Year Royalty Pharma Royalty Pharma [Member] Royalty Pharma member. Long-term Debt, Type Longterm Debt Type [Axis] Income Statement Location Income Statement Location [Domain] Valuation Technique, Option Pricing Model Valuation Technique Option Pricing Model [Member] Prepaid expenses and other current assets Increase Decrease In Prepaid Expense Other Current Assets Increase decrease in prepaid expense other current assets. Class Of Warrant Or Right [Table] Class Of Warrant Or Right [Table] Preferred stock, shares authorized Preferred Stock Shares Authorized Exercisable at the end of the period (in dollars per share) Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price Increase (Decrease) in Accrued Liabilities, Total Accrued expenses and other current liabilities Increase Decrease In Accrued Liabilities Minimum [Member] Minimum [Member] Thereafter Lessee Operating Lease Liability Payments Due After Year Two Lessee, operating lease, liability, payments, due after year three. Fair value of warrants estimated Warrants Not Settleable In Cash Fair Value Disclosure Measurement Input, Risk Free Interest Rate Measurement Input Risk Free Interest Rate [Member] Shares of common stock to purchase by warrant Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights Cash flows from financing activities: Net Cash Provided By Used In Financing Activities [Abstract] Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total Total unrecognized compensation costs Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Debt Instrument Debt Instrument [Axis] Entity Filer Category Entity Filer Category Document Fiscal Year Focus Document Fiscal Year Focus Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Fair value of common stock on grant date (in dollars per share) Weighted average grant date fair value per share of common stock Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value Retained Earnings (Accumulated Deficit), Ending Balance Retained Earnings (Accumulated Deficit), Beginning Balance Retained Earnings (Accumulated Deficit), Total Accumulated deficit Accumulated deficit Retained Earnings Accumulated Deficit Maximum [Member] Maximum [Member] Entity Central Index Key Entity Central Index Key Restricted Cash Cash And Cash Equivalents Restricted Cash And Cash Equivalents Policy Payables And Accruals [Abstract] Measurement Input Type Measurement Input Type [Axis] Cash and Cash Equivalents Cash And Cash Equivalents Policy [Text Block] Entity Tax Identification Number Entity Tax Identification Number Equity Component Equity Component [Domain] Preferred stock, par value (in dollars per share) Preferred Stock Par Or Stated Value Per Share Volatility Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Expected dividend Alternative Investment Measurement Expected Dividend Payments Alternative investment measurement expected dividend payments. Stock split conversion ratio Stockholders' Equity Note, Stock Split, Conversion Ratio Weighted-average period over which unrecognized compensation costs is expected to be recognized Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1 Development-stage Proprietary Compounds In Process Research And Development [Member] Statement [Table] Statement [Table] Entity File Number Entity File Number Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Lessee Lease Description [Line Items] Lessee Lease Description [Line Items] Accumulated Deficit Retained Earnings [Member] Increase (Decrease) in Accounts Payable, Total Accounts payable Increase Decrease In Accounts Payable Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Outstanding shares of common stock reverse stock splits Adjustments due to the rounding impact from the reverse stock split for fractional shares (in shares) Stock Issued During Period, Shares, Reverse Stock Splits Document Entity Information [Abstract] Current liabilities Liabilities Current [Abstract] Stock Award Plan and Stock-Based Compensation Disclosure Of Compensation Related Costs Share Based Payments [Text Block] Commitments and Contingencies Commitments And Contingencies Disclosure [Text Block] Total operating lease liabilities at June 30, 2022 Operating Lease Liability Common Stock Common Stock [Member] Professional fees Accrued Professional Fees Current Cover [Abstract] Cover [Abstract] Credit Facility Credit Facility [Domain] Related Party Transaction [Domain] Statement Of Stockholders Equity [Abstract] Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] Restricted Stock Units Restricted Stock Units R S U [Member] Document Transition Report Document Transition Report Research and Development Expense, Total Research and development Research And Development Expense Stock based compensation expense Allocated Share Based Compensation Expense Statement Of Financial Position [Abstract] Office Sublease Agreement Office Sublease Agreement [Member] Office sublease agreement. Dividend yield (as a percent) Dividend yield Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate Amortization of right-of-use assets Operating Lease Right Of Use Asset Amortization Expense Stockholders' (deficit) equity Stockholders Equity [Abstract] Nature of Operations and Liquidity Nature Of Operations Proceeds from Issuance or Sale of Equity, Total Net proceeds after deducting sales commissions and offering costs payable Proceeds From Issuance Or Sale Of Equity Reverse Stock Split Reverse Stock Split [Policy Text Block] Reverse Stock Split [Policy Text Block] Computation of Basic and Diluted Loss Per Share Schedule Of Earnings Per Share Basic And Diluted Table [Text Block] Exercised (in dollars per share) Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price Changes in operating assets and liabilities Increase Decrease In Operating Capital [Abstract] Entity Common Stock, Shares Outstanding Entity Common Stock Shares Outstanding Award Type Award Type [Axis] Entity Shell Company Entity Shell Company Common stock, average price per share Sale Of Stock Price Per Share Liabilities and Stockholders' (Deficit) Equity Liabilities And Stockholders Equity [Abstract] Entity Incorporation, State or Country Code Entity Incorporation State Country Code Rick Russell President [Member] Net Loss Per Share of Common Stock Earnings Per Share [Text Block] Counterparty Name Repurchase Agreement Counterparty Name [Domain] Amendment Flag Amendment Flag Product and Service Product Or Service [Axis] Cash and Cash Equivalents, at Carrying Value, Ending Balance Cash and Cash Equivalents, at Carrying Value, Beginning Balance Cash and Cash Equivalents, at Carrying Value, Total Cash and cash equivalents Cash And Cash Equivalents At Carrying Value Recent Accounting Pronouncements New Accounting Pronouncements Policy Policy [Text Block] Title of Individual Title Of Individual With Relationship To Entity [Domain] Common stock exchanged for PRSUs Common Stock Exchanged For P R S U S Liability related to the sale of future royalties Liability Related To The Sale Of Future Royalties Liability related to the sale of future royalties. Antidilutive Securities, Name Antidilutive Securities Name [Domain] Collaborative Arrangement and Arrangement Other than Collaborative Type Of Arrangement [Axis] Option Exchange Program [Member] Option Exchange Program [Member] Option exchange program. Total Intrinsic Value Exercisable Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1 Schedule of Stock-Based Compensation Expense Included in the Company's Consolidated Statements of Operations Schedule Of Compensation Cost For Share Based Payment Arrangements Allocation Of Share Based Compensation Costs By Plan Table [Text Block]