Entity Central Index Key Document Entity Information [Abstract] Entity Registrant Name Entity Registrant Name Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Entity Filer Category Entity Filer Category Document Type Document Type Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Amendment Flag Amendment Flag Entity Well-known Seasoned Issuer Entity Well Known Seasoned Issuer Entity Voluntary Filers Entity Voluntary Filers Entity Current Reporting Status Entity Current Reporting Status Entity Public Float Entity Public Float Entity Common Stock, Shares Outstanding Entity Common Stock Shares Outstanding Trading Symbol Trading Symbol Deferred related party revenue, current. Statement Of Financial Position [Abstract] Assets Assets [Abstract] Current assets Assets Current [Abstract] Cash and cash equivalents Cash And Cash Equivalents At Carrying Value Marketable securities Marketable Securities Current Restricted cash Restricted Cash And Cash Equivalents At Carrying Value Prepaid expenses and other current assets Prepaid Expense Current Total current assets Assets Current Equipment, net Property Plant And Equipment Net In-process research and development Intangible Assets Net Excluding Goodwill Goodwill Goodwill Total assets Assets Liabilities and Stockholders’ Equity Liabilities And Stockholders Equity [Abstract] Current liabilities Liabilities Current [Abstract] Notes payable -current portion Notes Payable Current Accounts payable Accounts Payable Current Accrued expenses and other current liabilities Accounts Payable And Other Accrued Liabilities Current Accrued collaborative expenses - related party Deferred Related Party Revenue Current Total current liabilities Liabilities Current Notes payable -noncurrent Long Term Notes Payable Deferred taxes Deferred Tax Liabilities Noncurrent Total liabilities Liabilities Commitments and contingencies Commitments And Contingencies Stockholders’ equity Stockholders Equity [Abstract] Preferred stock; $.0001 par value; 100,000,000 shares authorized; none issued or outstanding as of December 31, 2016 and 2015, respectively Preferred Stock Value Common stock; $.0001 par value; 125,000,000 shares authorized; 35,024,002 and 24,721,143 shares issued and outstanding as of December 31, 2016 and 2015, respectively Common Stock Value Additional paid-in capital Additional Paid In Capital Common Stock Accumulated deficit Retained Earnings Accumulated Deficit Total stockholders’ equity Stockholders Equity Total liabilities and stockholders’ equity Liabilities And Stockholders Equity Preferred stock, par value (in dollars per share) Preferred Stock Par Or Stated Value Per Share Preferred stock, shares authorized Preferred Stock Shares Authorized Preferred stock, shares issued Preferred Stock Shares Issued Preferred stock, shares outstanding Preferred Stock Shares Outstanding Common stock, par value (in dollars per share) Common Stock Par Or Stated Value Per Share Common stock, shares authorized Common Stock Shares Authorized Common stock, shares issued Common Stock Shares Issued Common stock, shares outstanding Common Stock Shares Outstanding Income Statement [Abstract] Expenses Operating Expenses [Abstract] Research and development Research And Development Expense General and administrative General And Administrative Expense Total expenses Operating Expenses Loss from operations Operating Income Loss Foreign exchange (losses) gains Foreign Currency Transaction Gain Loss Before Tax Investment income Investment Income Interest Interest expense Interest Income Expense Nonoperating Net Net loss Net Income Loss Net loss per share, basic and diluted Earnings Per Share Basic And Diluted Weighted average shares outstanding, basic and diluted Weighted Average Number Of Share Outstanding Basic And Diluted Stock issued during period value exercise of warrants. Stock issued during period shares exercise of warrants. Statement Of Stockholders Equity [Abstract] Statement [Table] Statement [Table] Equity Components Statement Equity Components [Axis] Equity Component Equity Component [Domain] Common Stock Common Stock [Member] Additional Paid-in Capital Additional Paid In Capital [Member] Accumulated Deficit Retained Earnings [Member] Sale of Stock Subsidiary Sale Of Stock [Axis] Sale of Stock Sale Of Stock Name Of Transaction [Domain] Initial public offering and concurrent private placements. Initial Public Offering and Concurrent Private Placements Initial Public Offering And Concurrent Private Placements [Member] Private Placement Private Placement [Member] Public offering. Public Offering Public Offering [Member] Statement [Line Items] Statement [Line Items] Balance Balance (in shares) Issuance of shares for business acquisition Stock Issued During Period Value Acquisitions Issuance of shares for business acquisition (in shares) Stock Issued During Period Shares Acquisitions Issuance of common stock and warrants, net of issuance costs Stock Issued During Period Value New Issues Issuance of common stock and warrants, net of issuance costs (in shares) Stock Issued During Period Shares New Issues Vesting of common shares issued Stock Issued During Period Value Share Based Compensation Gross Vesting of common shares issued (in shares) Stock Issued During Period Shares Share Based Compensation Gross Issuance of warrants pursuant to loan agreement Adjustments To Additional Paid In Capital Warrant Issued Exercise of common stock warrants Stock Issued During Period Value Exercise Of Warrants Exercise of common stock warrants (in shares) Stock Issued During Period Shares Exercise Of Warrants Exercise of stock options Stock Issued During Period Value Stock Options Exercised Exercise of stock options (in shares) Stock Issued During Period Shares Stock Options Exercised Stock-based compensation Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value Conversion of debt and interest to common stock Stock Issued During Period Value Conversion Of Convertible Securities Net Of Adjustments Conversion of debt and interest to common stock (in shares) Stock Issued During Period Shares Conversion Of Convertible Securities Net loss Balance Balance (in shares) Issuance cost Adjustments To Additional Paid In Capital Stock Issued Issuance Costs Increase decrease in prepaid expense other current assets. Represents the gross proceeds received from the issuance of common stock during the period. Cost paid in connection with private placement. The amount of deferred tax liability that the Entity assumes in acquiring a business or in consideration for an asset received in a noncash (or part noncash) acquisition. The amount of goodwill that the Entity acquires in a noncash (or part noncash) acquisition. Represents the amount associated with the acquisition of a business when the cash held by the acquired business exceeds the cash payments to acquire the business. Statement Of Cash Flows [Abstract] Cash flows from operating activities: Net Cash Provided By Used In Operating Activities Continuing Operations [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Depreciation and amortization Depreciation Depletion And Amortization Amortization of debt discount recorded as interest expense Amortization Of Debt Discount Premium Amortization of marketable securities premium Investment Income Amortization Of Premium Stock-based compensation expense Share Based Compensation Change in fair value of derivative Unrealized Gain Loss On Derivatives Changes in operating assets and liabilities Increase Decrease In Operating Capital [Abstract] Prepaid expenses and other current assets Increase Decrease In Prepaid Expense Other Current Assets Accounts payable Increase Decrease In Accounts Payable Accrued expenses and other current liabilities Increase Decrease In Accrued Liabilities Accrued collaborative expenses Increase Decrease In Deferred Revenue Other noncurrent liabilities Increase Decrease In Other Noncurrent Liabilities Net cash used in operating activities Net Cash Provided By Used In Operating Activities Continuing Operations Cash flows from investing activities: Net Cash Provided By Used In Investing Activities Continuing Operations [Abstract] Purchases of marketable securities Payments To Acquire Marketable Securities Proceeds from the maturity and redemption of marketable securities Proceeds From Sale And Maturity Of Marketable Securities Cash acquired in business combination Cash Acquired From Acquisition Restricted cash Increase Decrease In Restricted Cash Purchases of equipment Payments To Acquire Property Plant And Equipment Net cash provided by (used in) investing activities Net Cash Provided By Used In Investing Activities Continuing Operations Cash flows from financing activities: Net Cash Provided By Used In Financing Activities Continuing Operations [Abstract] Proceeds from sale of common stock in public offering Gross Proceeds From Issuance Of Common Stock Proceeds from sales of common stock in initial public offering Proceeds From Issuance Initial Public Offering Costs paid in connection with public offering Payments Of Stock Issuance Costs Proceeds from sales of common stock in private placement Proceeds From Issuance Of Private Placement Costs paid in connection with private placements Costs Paid In Connection With Private Placement Proceeds from exercise of common stock warrants Proceeds From Warrant Exercises Proceeds from exercise of stock options Proceeds From Stock Options Exercised Proceeds from notes payable Proceeds From Notes Payable Costs paid in connection with notes payable Repayments Of Notes Payable Repayments of notes payable Repayments Of Senior Debt Net cash provided by financing activities Net Cash Provided By Used In Financing Activities Continuing Operations Net increase (decrease) in cash and cash equivalents Net Cash Provided By Used In Continuing Operations Cash and cash equivalents Cash And Cash Equivalents At Carrying Value [Abstract] Beginning of year End of year Supplemental disclosure Supplemental Cash Flow Information [Abstract] Cash paid for interest Interest Paid Supplemental disclosure of noncash investing and financing activities Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract] Common stock issued as consideration for business combination Stock Issued1 Plus liabilities assumed: Noncash Or Part Noncash Acquisition Value Of Liabilities Assumed [Abstract] Accrued expenses and other Noncash Or Part Noncash Acquisition Payables Assumed1 ProteoSys milestone payable Noncash Or Part Noncash Acquisition Other Liabilities Assumed1 Deferred tax liability Noncash Or Part Noncash Acquisition Deferred Tax Liability Assumed Less assets acquired: Noncash Or Part Noncash Acquisition Value Of Assets Acquired [Abstract] Prepaid expenses Noncash Or Part Noncash Acquisition Other Assets Acquired1 Equipment Noncash Or Part Noncash Acquisition Fixed Assets Acquired1 In-process research and development Noncash Or Part Noncash Acquisition Intangible Assets Acquired1 Goodwill Noncash Or Part Noncash Acquisition Goodwill Acquired Cash acquired in business merger Cash Acquired In Business Merger Conversion of debt and interest to common stock Debt Conversion Converted Instrument Amount1 Nature Of Operations And Liquidity Disclosure [Abstract] Nature of Operations and Liquidity Nature Of Operations Accounting Policies [Abstract] Significant Accounting Policies Significant Accounting Policies [Text Block] Business Combinations [Abstract] Business Combinations Business Combination Disclosure [Text Block] Payables And Accruals [Abstract] Accrued Expenses and Other Liabilities Accounts Payable And Accrued Liabilities Disclosure [Text Block] Earnings Per Share [Abstract] Net Loss Per Share of Common Stock Earnings Per Share [Text Block] Debt Disclosure [Abstract] Debt Debt Disclosure [Text Block] Co development and license agreement disclosure. Co Development And License Agreement Disclosure [Abstract] Co-Development and License Agreement Collaborative Arrangement Disclosure [Text Block] Stockholders Equity Note [Abstract] Stockholders' Equity Stockholders Equity Note Disclosure [Text Block] Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] Stock Award Plan and Stock-Based Compensation Disclosure Of Compensation Related Costs Share Based Payments [Text Block] Income Tax Disclosure [Abstract] Income Taxes Income Tax Disclosure [Text Block] Commitments And Contingencies Disclosure [Abstract] Commitments and Contingencies Commitments And Contingencies Disclosure [Text Block] Related Party Transactions [Abstract] Related Party Transactions Related Party Transactions Disclosure [Text Block] Quarterly Financial Information Disclosure [Abstract] Quarterly Results Quarterly Financial Information [Text Block] Subsequent Events [Abstract] Subsequent Events Subsequent Events [Text Block] Basis of Presentation Basis Of Accounting Policy Policy [Text Block] Consolidation Consolidation Policy [Text Block] Disclosure of accounting policy for significant risks and uncertainties. Significant Risks and Uncertainties Significant Risks And Uncertainties Policy [Text Block] Use of Estimates Use Of Estimates Cash and Cash Equivalents Cash And Cash Equivalents Policy [Text Block] Restricted Cash Cash And Cash Equivalents Restricted Cash And Cash Equivalents Policy Marketable Securities Marketable Securities Policy Research and Development Costs Research And Development Expense Policy In-Process Research and Development In Process Research And Development Policy Stock-Based Compensation Share Based Compensation Option And Incentive Plans Policy Foreign Currency Transactions Foreign Currency Transactions And Translations Policy [Text Block] Loss Per Share Earnings Per Share Policy [Text Block] Income Taxes Income Tax Policy [Text Block] Concentration of Credit Risk Concentration Risk Credit Risk Equipment Property Plant And Equipment Policy [Text Block] Long-Lived Assets Impairment Or Disposal Of Long Lived Assets Policy [Text Block] Business Combinations Business Combinations Policy Goodwill Goodwill And Intangible Assets Goodwill Policy Fair Value of Financial Instruments Fair Value Of Financial Instruments Policy Segment Information Segment Reporting Policy Policy [Text Block] Comprehensive Loss Comprehensive Income Policy Policy [Text Block] Recent Accounting Pronouncements New Accounting Pronouncements Policy Policy [Text Block]