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Adjustments to reconcile net loss to net cash used in operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Income Statement Location Statement of Income Location, Balance [Domain] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Title and Position [Domain] Deferred public offering costs. Deferred public offering costs Common Stock, Value, Issued, Ending Balance Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Total Common Stock, Value, Issued Common stock; $0.0001 par value; 125,000,000 shares authorized; 6,993,406 shares issued and outstanding as of March 31, 2025 and December 31, 2024 Investment income Investment Income, Interest Pre-funded warrants issuable nominal consideration per share. Pre-Funded Warrants Issuable Nominal Consideration Per Share Pre-funded warrants issuable nominal consideration per share Schedule of Accrued Expenses and Other Liabilities Schedule of Accrued Liabilities [Table Text Block] Commitments and contingencies (Note 8) Commitments and Contingencies Weighted average shares of common stock outstanding - diluted Weighted Average Number of Shares Outstanding, Diluted, Total Weighted Average Number of Shares Outstanding, Diluted Weighted average shares outstanding, diluted Reverse Stock Split Reverse Stock Split [Policy Text Block] Reverse Stock Split [Policy Text Block] SIGNIFICANT ACCOUNTING POLICIES Significant Accounting Policies Significant Accounting Policies [Text Block] Summarizes of Reportable Segment's Financial Information Schedule of Segment Reporting Information, by Segment [Table Text Block] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number PRSU'S vested Entity Small Business Entity Small Business Segment Reporting Information [Line Items] Foreign Currency Transaction Gain (Loss), before Tax, Total Gain (Loss), Foreign Currency Transaction, before Tax Foreign exchange losses Foreign exchange (losses) gains Credit Facility Credit Facility [Axis] Expired (in dollar per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Maximum beneficial ownership limitation. Maximum Beneficial Ownership Limitation Maximum beneficial ownership limitation Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Outstanding at the beginning of period (in dollars per share) Outstanding at the end of the period (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Initial Upfront Payment Amortized Interest Expense Potential Milestone Payments Received Initial upfront payment amortized interest expense potential milestone payments received Initial upfront payment amortized interest expense potential milestone payments received Common stock exchanged for PRSUs Common Stock Exchanged For P R S U S Common Stock Exchanged For P R S U S Potential Future Milestone Payment Received Potential future milestone payment received. Potential future milestone payments received Liability related to the sale of future royalties Liability Related To The Sale Of Future Royalties Liability related to the sale of future royalties. Income (Loss) from Continuing Operations, Net of Tax, Attributable to Parent Income (Loss) from Continuing Operations, Net of Tax, Attributable to Parent, Total Net income from continuing operations Subsequent Events Accounts Payable, Current, Total Accounts payable Accounts Payable, Current Option Exchange Program [Member] Option Exchange Program [Member] Option exchange program. Increase (Decrease) in Accrued Liabilities, Total Accrued expenses and other current liabilities Increase (Decrease) in Accrued Liabilities