100000 - Document - Document and Entity Information link:presentationLink link:calculationLink link:definitionLink 100010 - Statement - Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 100020 - Statement - Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 100030 - Statement - Consolidated Statements of Operations link:presentationLink link:calculationLink link:definitionLink 100040 - Statement - Consolidated Statements of Stockholders' (Deficit) Equity link:presentationLink link:calculationLink link:definitionLink 100050 - Statement - Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 100060 - Disclosure - Nature of Operations and Liquidity link:presentationLink link:calculationLink link:definitionLink 100070 - Disclosure - Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 100080 - Disclosure - Accrued Expenses and Other Liabilities link:presentationLink link:calculationLink link:definitionLink 100090 - Disclosure - Net Loss Per Share of Common Stock link:presentationLink link:calculationLink link:definitionLink 100100 - Disclosure - Sale of Future Royalties link:presentationLink link:calculationLink link:definitionLink 100110 - Disclosure - Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 100120 - Disclosure - Stock Award Plan and Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 100130 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 100140 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 100150 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 100160 - Disclosure - Related Party Transactions link:presentationLink link:calculationLink link:definitionLink 100170 - Disclosure - Subsequent Events link:presentationLink link:calculationLink link:definitionLink 100180 - Disclosure - Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 100190 - Disclosure - Significant Accounting Policies (Tables) link:presentationLink link:calculationLink link:definitionLink 100200 - Disclosure - Accrued Expenses and Other Liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 100210 - Disclosure - Net Loss Per Share of Common Stock (Tables) link:presentationLink link:calculationLink link:definitionLink 100220 - Disclosure - Sale of Future Royalties (Tables) link:presentationLink link:calculationLink link:definitionLink 100230 - Disclosure - Stock Award Plan and Stock-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 100240 - Disclosure - Income Taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 100250 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 100260 - Disclosure - NATURE OF OPERATIONS AND LIQUIDITY - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100270 - Disclosure - SIGNIFICANT ACCOUNTING POLICIES - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100280 - Disclosure - SIGNIFICANT ACCOUNTING POLICIES - Fair Value of Cash Equivalents and Marketable Securities Measured on Recurring Basis and Determined by Valuation Techniques (Details) link:presentationLink link:calculationLink link:definitionLink 100290 - Disclosure - ACCRUED EXPENSES AND OTHER LIABILITIES - Accrued Expenses and Other Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 100300 - Disclosure - NET LOSS PER SHARE OF COMMON STOCK - Computation of Basic and Diluted Loss Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 100310 - Disclosure - NET LOSS PER SHARE OF COMMON STOCK - Securities Excluded from Calculation of Weighted Average Shares Outstanding as their Effect is Antidilutive (Details) link:presentationLink link:calculationLink link:definitionLink 100320 - Disclosure - Sale of Future Royalties - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100330 - Disclosure - Sale of Future Royalties - Summary of Activity of the Royalty Obligation (Details) link:presentationLink link:calculationLink link:definitionLink 100340 - Disclosure - STOCKHOLDERS' EQUITY - At-the-Market Equity Offering Program - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100350 - Disclosure - STOCKHOLDERS' EQUITY - Term Loan Warrants - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100360 - Disclosure - STOCK AWARD PLAN AND STOCK-BASED COMPENSATION - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100370 - Disclosure - STOCK AWARD PLAN AND STOCK-BASED COMPENSATION - Stock Option Activity for Employees and Non-Employees (Details) link:presentationLink link:calculationLink link:definitionLink 100380 - Disclosure - STOCK AWARD PLAN AND STOCK-BASED COMPENSATION - Summary of Assumptions Used in Black Scholes Model to Estimate Fair Value of Stock Options (Details) link:presentationLink link:calculationLink link:definitionLink 100390 - Disclosure - STOCK AWARD PLAN AND STOCK-BASED COMPENSATION - Schedule of Stock-Based Compensation Expense Included in the Company's Consolidated Statements of Operations (Details) link:presentationLink link:calculationLink link:definitionLink 100400 - Disclosure - INCOME TAXES - Schedule of Provision for Federal, Foreign and State Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 100410 - Disclosure - INCOME TAXES - Net Deferred Tax Assets (Liabilities) (Details) link:presentationLink link:calculationLink link:definitionLink 100420 - Disclosure - INCOME TAXES - Schedule of Effective Income Tax Rate Reconciliation (Details) link:presentationLink link:calculationLink link:definitionLink 100430 - Disclosure - INCOME TAXES - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100440 - Disclosure - LEASES - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100450 - Disclosure - LEASES - Future Minimum Lease Payments Under Non-cancelable Operating Lease (Details) link:presentationLink link:calculationLink link:definitionLink 100460 - Disclosure - RELATED PARTY TRANSACTIONS - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink