Entity Address, City or Town Entity Address, City or Town Performance-Based Restricted Stock Units Performance-based Restricted Stock Units Performance Based Restricted Stock Units [Member] Performance-based restricted stock units. Earnings Per Share [Abstract] Number of tranches Number Of Tranches Number of tranches. Lease commencement date Lease Commencement Date Lease commencement date. Schedule of Accrued Expenses and Other Liabilities Schedule of Accrued Liabilities [Table Text Block] Significant Risks and Uncertainties Significant Risks And Uncertainties Policy [Text Block] Disclosure of accounting policy for significant risks and uncertainties. Sales of common stock, value Stock Issued During Period, Value, New Issues Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Dividend yield (as a percent) Dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Sale Of Future Royalties [Abstract] Sale of future royalties. Amendment Flag Amendment Flag Subsequent Event Type [Domain] Goodwill, Ending Balance Goodwill, Beginning Balance Goodwill, Total Goodwill Goodwill Upfront payment from the sale of future royalties Upfront Payment Paid Upfront payment paid. Document Quarterly Report Document Quarterly Report Refundable regulatory fee Refundable regulatory fee current. Refundable regulatory fee current Vacation pay Accrued Vacation, Current Monthly rental rate Monthly Rental Rate Monthly rental rate. Statement [Table] Statement [Table] Preferred Stock, Shares Outstanding, Ending Balance Preferred Stock, Shares Outstanding, Beginning Balance Preferred stock, shares outstanding Preferred Stock, Shares Outstanding Common Stock, Capital Shares Reserved for Future Issuance Eligible for sale of equity Nature of Operations and Liquidity Nature of Operations [Text Block] Product and Service Product and Service [Axis] Annual interest rate on interest expense Annual Interest Rate On Interest Expense Annual interest rate on interest expense. Fair value of warrants estimated Warrants Not Settleable in Cash, Fair Value Disclosure Common Stock Options Employee Stock Option Share-Based Payment Arrangement, Option [Member] Total liabilities and stockholders' (deficit) equity Liabilities and Equity Plan Name Plan Name [Domain] Research and development costs and other accrued expenses Accrued Research And Development Costs And Other Expenses Current Represents the carrying value, as of the balance sheet date, of obligations incurred through that date and payable for research and development costs. It is used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle, if longer). Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Income Statement [Abstract] Reverse stock split Stockholders' Equity, Reverse Stock Split Total current liabilities Liabilities, Current Loan and Security Agreement Loan And Security Agreement [Member] Loan and security agreement. Cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations [Abstract] Accrued Expenses and Other Liabilities Accounts Payable and Accrued Liabilities Disclosure [Text Block] Reclassification [Line Items] Preferred stock, shares authorized Preferred Stock, Shares Authorized Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Proceeds from Issuance or Sale of Equity, Total Net proceeds after deducting sales commissions and offering costs payable Proceeds from Issuance or Sale of Equity Aggregate eligible amount for sale of equity Entity Small Business Entity Small Business Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Ending Balance Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Beginning Balance Total cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Total current assets Assets, Current Indefinite-lived Intangible Assets Indefinite-Lived Intangible Assets [Axis] Weighted average shares of common stock outstanding - basic Weighted Average Number of Shares Outstanding, Basic, Total Weighted Average Number of Shares Outstanding, Basic Weighted average shares outstanding, basic Liability related to the sale of future royalties Liability Related To Sale Of Future Royalties Liability related to the sale of future royalties. City Area Code City Area Code Total Intrinsic Value Outstanding at the begining of period Total Intrinsic Value Outstanding at the end of period Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Forfeited (in shares) PRSU'S cancelled Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Share-Based Payment Arrangement [Abstract] Total liabilities Liabilities Document Period End Date Document Period End Date Lease Contractual Term [Domain] Fair value of common stock on grant date (in dollars per share) Weighted average grant date fair value per share of common stock Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Non-cash interest expense for the sale of future royalties Non Cash Interest Expense For The Sale Of Future Royalties Non-cash interest expense for the sale of future royalties Statistical Measurement Statistical Measurement [Axis] Sale of stock issue date Sale of Stock, Transaction Date Subsequent Event [Line Items] Total assets Assets Earnings Per Share, Diluted, Total Earnings Per Share, Diluted Net loss per share, diluted Rick Russell President [Member] Securities Excluded from Calculation of Weighted Average Shares Outstanding as their Effect is Antidilutive Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Exercise price per unit Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Exercise Price Expected life Alternative Investment Measurement Expected Term Alternative investment measurement expected term. Entity Address, Postal Zip Code Entity Address, Postal Zip Code Document Fiscal Period Focus Document Fiscal Period Focus Class Of Warrant Or Right [Table] Class of Warrant or Right [Table] Increase (Decrease) in Regulatory Liabilities Refundable regulatory fee Preferred stock; $0.0001 par value; 100,000,000 shares authorized; none issued or outstanding as of March 31, 2023 and December 31, 2022, respectively Preferred Stock, Value, Issued, Ending Balance Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Total Preferred Stock, Value, Issued Sale Of Future Royalties [Table] Sale Of Future Royalties [Table] Sale of future royalties. APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total Stock-based compensation APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Investment income Investment Income, Interest Counterparty Name Counterparty Name [Domain] Net cash provided by financing activities Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities Statement of Financial Position [Abstract] Term Loan Notes Payable to Banks [Member] Entity File Number Entity File Number Open Market Sale Agreement with Jefferies LLC. Open Market Sale Agreement with Jefferies LLC Statement of Cash Flows [Abstract] Valuation Approach and Technique Valuation Approach and Technique [Domain] Number of licenses acquired Number Of Licenses Acquired Number of licenses acquired. Shares of common stock to purchase by warrant Class of Warrant or Right, Number of Securities Called by Warrants or Rights Class Of Warrant Or Right [Line Items] Class of Warrant or Right [Line Items] Non-cash incremental stock-based compensation cost Share Based Goods And Services Non Cash Incremental Stock Based Compensation Cost Share based goods and services non cash incremental stock based compensation cost. Statistical Measurement Statistical Measurement [Domain] Statement of Stockholders' Equity [Abstract] Accrued bonus Accrued Bonuses, Current Stockholders' Equity Note [Abstract] Subsequent Events [Abstract] Sales Agreement Sales Agreement [Member] Sales agreement. Weighted-Average Remaining Contractual Term Exercisable (Years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Long-term Debt, Type Long-Term Debt, Type [Axis] Measurement Input, Expected Dividend Payment Measurement Input, Expected Dividend Payment [Member] Antidilutive Securities Antidilutive Securities [Axis] Expiration anniversary date of issuance Expiration Anniversary Date Of Issuance Expiration anniversary date of issuance. Aggregate principal amount Line of Credit Facility, Maximum Borrowing Capacity Preferred stock, par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share Credit Facility Credit Facility [Domain] Subsequent Events Weighted average shares of common stock outstanding - diluted Weighted Average Number of Shares Outstanding, Diluted, Total Weighted Average Number of Shares Outstanding, Diluted Weighted average shares outstanding, diluted Credit Facility Credit Facility [Axis] General and Administrative General and Administrative Expense [Member] Sale of stock maximum value of shares issued in transaction. Sale of stock maximum value of shares issued in transaction U S Food And Drug Administration [Member] FDA [Member] Current Fiscal Year End Date Current Fiscal Year End Date Nature Of Operations And Liquidity [Line Items] Nature Of Operations And Liquidity [Line Items] Nature of operations and liquidity. Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total Beginning of period End of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Entity Address, Address Line One Entity Address, Address Line One Capitalized Computer Software, Amortization Amortization of capitalized software Lease expire date Lease Expiration Date 2013 Equity Incentive Plan Twenty Thirteen Equity Incentive Plan [Member] Twenty thirteen equity incentive plan. Preferred Stock, Shares Issued, Total Preferred stock, shares issued Preferred Stock, Shares Issued Aggregate offering price of common stock preferred stock debt securities and warrants. Maximum aggregate offering price Sale Of Future Royalties [Line Items] Sale Of Future Royalties [Line Items] Sale of future royalties. Capitalized Computer Software, Net, Ending Balance Capitalized Computer Software, Net, Beginning Balance Capitalized Computer Software, Net, Total Capitalized software, net Capitalized Computer Software, Net Common stock issued and sold Stock Issued During Period, Shares, New Issues Nature Of Operations And Liquidity [Table] Nature Of Operations And Liquidity [Table] Disclosure pertaining to nature of operations and liquidity. Lease description Lease Description Lease description. Forfeited (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Loss from operations Operating Income (Loss) User fees refund received. User fees refund received Additional Paid in Capital, Common Stock, Ending Balance Additional Paid in Capital, Common Stock, Beginning Balance Additional paid-in capital Additional Paid in Capital, Common Stock Regus Regus [Member] Regus. Professional fees Accrued Professional Fees, Current Entity Filer Category Entity Filer Category Total expenses Operating Expenses Term A Loans Term A Loans [Member] Term A loans. Warrant Warrants Not Settleable Cash [Member] Warrants Not Setteleable Cash . Entity Current Reporting Status Entity Current Reporting Status Total Intrinsic Value Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Summary of Activity of the Royalty Obligation Summary Of Activity Of The Royalty Obligation Table [Text Block] Summary of activity of the royalty obligation. Stockholders' Equity Stockholders' Equity Note Disclosure [Text Block] Total stockholders' (deficit) equity Balance Balance Stockholders' Equity Attributable to Parent Development-stage Proprietary Compounds In Process Research and Development [Member] Entity Tax Identification Number Entity Tax Identification Number Income Statement Location Income Statement Location [Axis] Common stock; $0.0001 par value; 125,000,000 shares authorized; 5,340,193 shares issued and outstanding as of March 31, 2023 and December 31, 2022 Common Stock, Value, Issued, Ending Balance Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Total Common Stock, Value, Issued Retained Earnings (Accumulated Deficit), Ending Balance Retained Earnings (Accumulated Deficit), Beginning Balance Retained Earnings (Accumulated Deficit), Total Accumulated deficit Accumulated deficit Retained Earnings (Accumulated Deficit) Upfront payment for royalty interest sold Upfront Payment Upfront payment. Equity Components Equity Components [Axis] Refundable regulatory fee Refundable regulatory fee policy. Refundable regulatory fee Policy Text Block Refundable Regulatory Fee Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Prepaid Expense, Current, Total Prepaid expenses and other current assets Prepaid Expense, Current Entity Emerging Growth Company Entity Emerging Growth Company Related Party Transaction [Axis] Expenses Operating Expenses [Abstract] Measurement Input, Price Volatility Measurement Input, Price Volatility [Member] Schedule of Stock by Class [Table] Expected term (years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Lease rentable square feet Area of Real Estate Property Depreciation and amortization Depreciation, Depletion and Amortization, Nonproduction Depreciation, Depletion and Amortization, Nonproduction, Total Document Transition Report Document Transition Report Common stock, average price per share Sale of Stock, Price Per Share Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Accrued expenses and other current liabilities Accrued expenses and other current liabilities Accounts Payable and Other Accrued Liabilities, Current Net loss Net loss Net Income (Loss) Attributable to Parent Valuation Technique, Option Pricing Model Valuation Technique, Option Pricing Model [Member] Cash, cash equivalents, restricted cash and marketable securities Cash Cash Equivalents Restricted Cash And Marketable Securities Cash, cash equivalents, restricted cash and marketable securities. Additional Paid-in Capital Additional Paid-in Capital [Member] Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Entity Registrant Name Entity Registrant Name Cash and Cash Equivalents, at Carrying Value, Ending Balance Cash and Cash Equivalents, at Carrying Value, Beginning Balance Cash and Cash Equivalents, at Carrying Value, Total Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Net Loss Per Share of Common Stock Earnings Per Share [Text Block] Summary of Assumptions Used in Black Scholes Model to Estimate Fair Value of Stock Options Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Share-based Payment Arrangement, Noncash Expense, Total Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Equipment, net Property, Plant and Equipment, Net Property, Plant and Equipment, Net, Total Award Type Award Type [Domain] Statement [Line Items] Statement [Line Items] BP Reservoir BP Reservoir [Member] BP Reservoir. Title of 12(b) Security Title of 12(b) Security Increase (Decrease) in Accounts Payable, Total Accounts payable Increase (Decrease) in Accounts Payable Common Stock Common Stock [Member] Seltorexant Seltorexant [Member] Seltorexant. Restricted Cash Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Cash flows from operating activities: Net Cash Provided by (Used in) Operating Activities [Abstract] Equity Component Equity Component [Domain] Entity Address, State or Province Entity Address, State or Province Net decrease in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Document Type Document Type Entity Shell Company Entity Shell Company Stock based compensation expense Share-Based Payment Arrangement, Expense Loss Contingencies [Line Items] Loss Contingencies [Line Items] Reclassification [Table] Nature Of Operations And Liquidity Disclosure [Abstract] Security Exchange Name Security Exchange Name Class of Stock [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] SIGNIFICANT ACCOUNTING POLICIES Significant Accounting Policies Significant Accounting Policies [Text Block] Net cash used in operating activities Net cash used in operating activities Net Cash Provided by (Used in) Operating Activities Weighted-average period over which unrecognized compensation costs is expected to be recognized Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Weighted-Average Remaining Contractual Term Outstanding (Years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Employees and Non-Employees Stock Option Employees And Non Employees Stock Option [Member] Employees and non-employees stock option. Commitments and Contingencies Disclosure [Abstract] Non-cash interest expense associated with the sale of future royalties Non Cash Interest Expense For Sale Of Future Royalties Amount of non-cash interest expense associated with the sale of future royalties. Measurement Input, Expected Term Measurement Input, Expected Term [Member] Operating lease, cost Operating Lease, Cost Restricted Stock Units Restricted Stock Units (RSUs) [Member] User fees paid. User Fees Paid User fees paid, related to roluperidone Consolidation Consolidation, Policy [Policy Text Block] Common Stock Warrants Warrant [Member] Schedule of Stock Option Activity for Employees and Non-Employees Share-Based Payment Arrangement, Option, Activity [Table Text Block] Recent Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Common stock, shares outstanding Balance (in shares) Balance (in shares) Common Stock, Shares, Outstanding Cash flows from investing activities: Net Cash Provided by (Used in) Investing Activities [Abstract] Sale of Future Royalties Sale Of Future Royalties Disclosure [Text Block] Sale of future royalties. Commitments and contingencies (Note 8) Commitments and Contingencies Common Stock, Shares, Issued, Total Common stock, shares issued Common Stock, Shares, Issued Minimum [Member] Minimum [Member] Additional milestone payments Potential Milestone Payments Restricted cash balances as collateral for corporate credit cards Restricted cash Restricted Cash, Current Exercisable at the end of the period (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Debt Instrument Debt Instrument [Axis] Stockholders' (deficit) equity Stockholders' Equity Attributable to Parent [Abstract] Royalty Pharma Royalty Pharma [Member] Royalty Pharma member. Foreign exchange losses Foreign Currency Transaction Gain (Loss), before Tax, Total Foreign Currency Transaction Gain (Loss), before Tax Counterparty Name Counterparty Name [Axis] Entity Address, Address Line Two Entity Address, Address Line Two Award Type Award Type [Axis] Prepaid expenses and other current assets Increase Decrease In Prepaid Expense Other Current Assets Increase decrease in prepaid expense other current assets. Subsequent Event Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total Total unrecognized compensation costs Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Related Party Transaction [Domain] Loss Contingencies [Table] Total intrinsic value of the stock options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Research and Development Expense, Total Research and development Research and Development Expense Entity Central Index Key Entity Central Index Key Accounting Policies [Abstract] Volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Available for future grant (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Stock Award Plan and Stock-Based Compensation Share-Based Payment Arrangement [Text Block] Subsequent Event [Table] General and Administrative Expense, Total General and administrative General and Administrative Expense Measurement Input Type Measurement Input Type [Domain] Outstanding at the beginning of period (in dollars per share) Outstanding at the end of the period (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Research and Development Research and Development Expense [Member] Adjustments to reconcile net loss to net cash used in operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Accumulated Deficit Retained Earnings [Member] Measurement Input Type Measurement Input Type [Axis] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Vesting percentage Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage Entity Interactive Data Current Entity Interactive Data Current Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplemental disclosure of non-cash financing activities Expected dividend Alternative Investment Measurement Expected Dividend Payments Alternative investment measurement expected dividend payments. Local Phone Number Local Phone Number Computation of Basic and Diluted Loss Per Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Vesting period of PRSUs after acceptance Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Lease Contractual Term [Axis] Exercisable at the end of the period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Shares issued Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Stock split conversion ratio Stockholders' Equity Note, Stock Split, Conversion Ratio Income Statement Location Income Statement Location [Domain] Measurement Input, Risk Free Interest Rate Measurement Input, Risk Free Interest Rate [Member] Minimum market value of listed securities required for continued listing Minimum Market Value of Listed Securities Required for Continued Listing Minimum market value of listed securities required for continued listing. Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Document Entity Information [Abstract] PRSU'S outstanding Outstanding at the beginning of period (in shares) Outstanding at the end of the period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Debt Instrument, Name Debt Instrument, Name [Domain] Document Fiscal Year Focus Document Fiscal Year Focus Deferred public offering costs included in accounts payable or in accrued expenses and other current liabilities. Deferred public offering costs included in accounts payable or in accrued expenses and other current liabilities Earnings Per Share, Basic, Total Earnings Per Share, Basic Net loss per share, basic Weighted-Average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Assets Assets [Abstract] Increase (Decrease) in Accrued Liabilities, Total Accrued expenses and other current liabilities Increase (Decrease) in Accrued Liabilities Reconciliation of the Condensed Consolidated Statements of Cash Flows to the Condensed Consolidated Balance Sheets Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents [Abstract] Previous Lease Previous Lease [Member] Previous lease. Shares Issuable Pursuant to Stock Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Liabilities and Stockholders' (Deficit) Equity Liabilities and Equity [Abstract] Outstanding shares of common stock reverse stock splits Adjustments due to the rounding impact from the reverse stock split for fractional shares (in shares) Stock Issued During Period, Shares, Reverse Stock Splits Antidilutive Securities, Name Antidilutive Securities, Name [Domain] Valuation Approach and Technique Valuation Approach and Technique [Axis] Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Current assets Assets, Current [Abstract] Common stock exercise price per share Class of Warrant or Right, Exercise Price of Warrants or Rights Payables and Accruals [Abstract] Changes in operating assets and liabilities Increase (Decrease) in Operating Capital [Abstract] Deferred public offering costs. Deferred public offering costs Cover [Abstract] Cover [Abstract] Product and Service Product and Service [Domain] Number of PSRUs vested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Current liabilities Liabilities, Current [Abstract] Maximum Maximum [Member] Maximum [Member] Net Cash Provided by (Used in) Investing Activities, Total Net cash provided by investing activities Net Cash Provided by (Used in) Investing Activities Reverse Stock Split Reverse Stock Split [Policy Text Block] Reverse Stock Split [Policy Text Block] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Schedule of Stock-Based Compensation Expense Included in the Company's Consolidated Statements of Operations Share-Based Payment Arrangement, Cost by Plan [Table Text Block] Use of Estimates Use of Estimates, Policy [Policy Text Block] Alternative investment, measurement input Alternative Investment, Measurement Input Number of shares of common stock authorized Common stock, shares authorized Common Stock, Shares Authorized Trading Symbol Trading Symbol Title of Individual Title of Individual [Domain] Subsequent Event Type [Axis] Risk free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Accounts Payable, Current, Total Accounts payable Accounts Payable, Current Common stock exchanged for PRSUs Common Stock Exchanged For P R S U S Plan Name Plan Name [Axis] Title of Individual Title of Individual [Axis] Liability related to the sale of future royalties Liability Related To The Sale Of Future Royalties Liability related to the sale of future royalties. Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Option Exchange Program [Member] Option Exchange Program [Member] Option exchange program. Granted (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Increase in number of shares authorized for issuance Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized Long-term Debt, Type Long-Term Debt, Type [Domain] Securities outstanding excluded from the calculation of weighted average shares outstanding Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Indefinite-lived Intangible Assets, Major Class Name Indefinite-Lived Intangible Assets, Major Class Name [Domain]